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Observing the expiration date is obligatory for the following medications: The wisdom suggests that if your life does depend on an outdated drug, and you must have 100% of the original strength, it is wise to follow the cliché "better safe than sorry".If your life does not depend on an expired drug -- such as you have headache, common cold, or constipation -- you may take the medication and see what happens.For example, if a company chooses a three year expiration date, it does not have to test beyond that for prolonged effectiveness.In fact, medication's potency gradually decreases starting from the moment of its manufacture.Injectable medications, which have become cloudy or discolored or show signs of precipitation should not be used.Certain medications have a narrow therapeutic index and little decreases in the pharmacological activity can result in serious consequences for patients.

Drugs in liquid form (solutions, suspensions) are not as stable as solid dosage forms (tablet, powder, capsule).The expiration date is only an assurance that the labeled potency will last at least until that date.Ongoing research shows that stored under optimal conditions, many drugs retain 90% of their potency for at least five years after the labeled expiration date, and sometimes longer.Contrary to common belief, there is little scientific evidence that expired drugs are toxic.There are virtually no reports of toxicity from degradation products of outdated drugs.

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